Immunization on Special Clinical Circumstances
Immunoglobulin may inhibit the immune response to vaccines, the duration of inhibition may vary with the indication for immunoglobulin and specific product; suggested interval is 3 months after Immunoglobulin administration.
Premature infants and infants with low birth weight, should be immunized at the usual chronological age in most cases. For premature infants with birth weight of less than 1 kg, Hepatitis B immunization should be delayed until the weight is 2 kg or more, or until approximately 2 months of age, except if the mother is HBsAg positive.
Immunocompromized may occur as primary immune-suppressive treatment or underlying diseases. Live vaccines generally are contraindicated.