BCG Vaccine (Freeze Dry)


Each ampoule of vaccine contains :
• Live attenuated Bacillus Calmette-Guerin 1.5 mg

Diluent consist of :
• Sodium Chloride 0.9 %

Active immunization against tuberculosis.

Mechanism of action
Stimulates the body to produce antibody against tuberculosis.

Side effects
The local reaction after BCG immunization is normal.

A small tender red swelling appears at the injection site, which than changes to a small vesicle, and than become ulcer in 2-4 weeks. This reaction usually disappears after 2-5 months, and generally in a child will result a scare with 2-10 mm in diameter.

Rarely the nodus and ulcer keep remaining. Occasionally, enlargement of axillary lymph nodes may appear in 2-4 months following immunization.

Very rarely, enlarged lymph nodes suppurate. Inadvertent subcutaneous injection may produce abscess formation and may lead to scarring.


  • Immune-deficiency.
  • Individuals infected with human immunodeficiency virus (HIV), both asymptomatic and symptomatic should not be vaccinated with BCG.

Drug interaction
Not reported.


  • BCG vials (freeze dried) must be stored at temperatures between +2°C to +8°C.
  • The vials of vaccine and the diluent should be transported together. However the diluent must not be frozen; it should be kept at room temperature.
  • The vaccine must be protected from light.
  • Expiry date 1 year.
  • Once reconstituted, BCG vaccine should be used immediately or within 3 hours, and the remaining vial vaccine must be discarded.